A cardioselective beta-adrenergic blocker possessing properties and potency similar to propranolol, but without a negative inotropic effect.
For the management of hypertention and long-term management of patients with angina pectoris.
Atenolol (Tenormin) is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Atenolol is used to treat angina (chest pain) and hypertension (high blood pressure). Atenolol is also used to lower the risk of death after a heart attack.
You should not use Atenolol if you have a serious heart condition such as “AV block,” very slow heartbeats, or heart failure.
Atenolol, a competitive beta(1)-selective adrenergic antagonist, has the lowest lipid solubility of this drug class.
Although it is similar to metoprolol, atenolol differs from pindolol and propranolol in that it does not have intrinsic sympathomimetic properties or membrane-stabilizing activity. Atenolol is used alone or with chlorthalidone in the management of hypertension and edema.
Mechanism of action
Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation.
This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles.
All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Atenolol.
Tell your doctor or pharmacist if you have any medical conditions.
Common atenolol side effects may include: dizziness, feeling tired or depressed mood.
Symptoms of an atenolol overdose include a slow heart beat, shortness of breath, fainting, dizziness, weakness, confusion, nausea, and vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.
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